To de-stress while I work, especially if I'm doing a repetitive task, I tune in to funny or interesting podcasts to help learn new things and get a laugh in the day. Lately I've been listening to "Stuff You Missed in History Class." There's a series of "Stuff" podcasts (stuff you're mother never told you, stuff you should know).
These ladies are really fun and they put a lot of research into whatever topic is on the podcast.